2014

125.Yu H, Lau K, Thon V, Autran CA, Jantscher-Krenn E, Xue M, Li Y, Sugiarto G, Qu J, Mu S, Ding L, Bode L, *Chen X. Synthetic disialyl hexasaccharides protect neonatal rats from necrotizing enterocolitis.Angew. Chem. Int. Ed. In press. PMID: 24848971. doi: 10.1002/anie.201403588

124.Meng X, Yao W, Cheng J, Zhang X, Jin L, Yu H, Chen X, *Wang F, *Cao H. Regioselective chemoenzymatic synthesis of ganglioside disialyl tetrasaccharide epitopes. J. Am. Chem. Soc. 2014,136, 5205-5208. PMID: 24649890. doi: 10.1021/ja5000609.

123.Khedri Z, Li Y, Muthana S, Muthana MM, Hsiao C-W, Yu H, *Chen X. Chemoenzymatic synthesis of sialosides containing C7-modified sialic acids and their application in sialidase substrate specificity studies. Carbohydr. Res. 2014, 389, 100-111. PMID: 24680514. DOI: 10.1016/j.carres.2014.02.021.

122.Halder S, Cotmore S, Heimburg-Molinaro J, Smith DF, Cummings RD, Chen X, Trollope AJ, North SJ, Haslam SM, Dell A, Tattersall P, McKenna R, Agbandje-McKenna M. Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition.PLoS One 2014, 9, e86909 (1-12). PMID: 24475195. PMCID: PMC3903596. DOI: 10.1371/journal.pone.0086909.

121.Hwang J, Yu H, Malekan H, Li Y, Sugiarto G, Thon V, Qu J, Nguyen V, Wu D, *Chen X. Highlyefficient one-pot multienzyme (OPME) synthesis of glycans with fluorous-tag assisted purification.Chem. Commun. 2014, 50 (24), 3159-3162. PMID:24473465. DOI:10.1039/C4CC00070F

120.Padler-Karavani V, Hurtado-Ziola N, Chang Y-C, Sonnenburg JL, Ronaghy A, Yu H, Verhagen A, Nizet V, Chen X, Varki N, Varki A, Angata T. Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates. FASEB Journal2014, 28, 1280-1293. PMID: 24308974. PMCID: PMC3929681. DOI  10.1096/fj.13-241497

119.Li Y, Yu H, Thon V, Chen Y, Muthana MM, Qu J, Hie L, *Chen X. Donor substrate promiscuity of theN-acetylglucosaminyltransferase activities of Pasteurella multocida heparosan synthase 2 (PmHS2) andEscherichia coli K5 KfiA. Appl. Microbiol. Biotechnol. 2014, 98, 1127-1134. PMID: 23661084. DOI 10.1007/s00253-013-4947-1

118.Fei Y, Landry JP, Li Y, Yu H, Lau K, Huang S, Chokhawala HA, Chen X, Zhu X. An optics-based variable-temperature assay system for characterizing thermodynamics of biomolecular reactions on solid support. Rev. Sci. Instrum. 201384, 114102, 1–9. PMID: 24289409. PMCID: PMC3838479. doi: 10.1063/1.4826352.

117.Huynh N, Aye A, Li Y, Yu H, Cao H, Tiwari VK, Shin D-W, Chen X, *Fisher AJ. Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida.Biochemistry 201352, 8570-8579. PMID: 24152047. PMCID: PMC3880309. DOI: 10.1021/bi4011754

116.Li L, Liu Y, Wan Y, Li Y, Chen X, Zhao W, Wang PG. Efficient enzymatic synthesis of guanosine 5′-diphosphate-sugars and derivatives. Org. Lett. 201315, 5528-5530. PMID: 24117142. PMCID: PMC3915774. doi: 10.1021/ol402585c

115.Chen Y, Li Y, Yu H, Sugiarto G, Thon V, Hwang J, Ding L, Hie L, *Chen X. Tailored design and synthesis of heparan sulfate oligosaccharide analogues using sequential one-pot multienzyme (OPME) systems. Angew. Chem. Int. Ed. 201352, 11852-11856. PMID: 24038939.  PMCID: PMC3943747. doi: 10.1002/anie.201305667.

114.Scobie L, Padler-Karavani V, Le Bas-Bernardet S, Crossan C, Blaha J, Matouskova M, Hector RD, Cozzi E, Vanhove B, Charreau B, Blancho G, Bourdais L, Tallachini M, Ribes JM, Yu H, Chen X, Kracikova J, Broz L, Hejnar J, Vesely P, Takeuchi Y, Varki A, Soulillou J-P. Long-term IgG response to porcine Neu5Gc-antigens without transmission of PERV in burn patients treated with porcine skin xenografts. J. Immunol. 2013191, 2907-2915. PMID: 23945141. PMCID: PMC3782708.

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