2011

93. Fei, Y.; Sun, Y.-S.; Li, Y.; Lau, K.; Yu, H.; Chokhawala, H. A.; Huang, S.; Landry, J. P.; Chen, X.; *Zhu, X.
Fluorescent labelling agents change affinity profiles of glycan-binding proteins.
Mol. BioSyst. 2011, 7, 3343-3352. PMID: 22009201. PMCID: PMC327173292.

92. Bradley, K. C.; Galloway, S. E.; Lasanajak, Y.; Song, X.; Heimburg-Molinaro, J.; Talekar, G. R.; Yu, H.; Chen, X.; Smith, D. F.; Cummings, R. D.; *Steinhauer, D. A.
Analysis of influenza virus hemagglutinin receptor binding mutants with limited receptor recognition properties and conditional replication characteristics.
J. Virol. 201185, 12387-12398. PMID: 21917953. PMCID: PMC3209400

91. Chen, Y.; Thon, V.; Li, Y.; Yu, H.; Ding, L.; Lau, K.; Qu, J.; Hie, L.; *Chen, X.
One-pot three-enzyme synthesis of UDP-GlcNAc derivatives. 
Chem. Commun. 
(Camb) 2011, 47, 10815-10817. PMID: 21863157. DOI:10.1039/C1CC14034E.[Supporting information]

90. Sugiarto, G., Lau, K.; Li, Y.; Khedri, Z.; Yu, H.; Le, D.-T.; *Chen, X.
Decreasing the sialidase activity of multifunctional Pasteurella multocida alpha 2-3-sialyltransferase 1 (PmST1) by site-directed mutagenesis. 
Mol. BioSyst. 
2011,7, 3021-3027. PMID: 21858283. DOI:10.1039/C1MB05182B.

89. Li, Y.; Yu, H.; Chen, Y.; Lau, K.; Cai, L.; Cao, H.; Tiwari, V. K.; Qu, J.; Thon, V.; Wang, P. G.; *Chen, X.
Substrate promiscuity of N-acetylhexosamine 1-kinases. 
Molecules 
201116, 6396-6407. Special Issue “Enzyme-catalyzed reactions”. PMID: 21799473.

88. Song, X.; Yu, H.; Chen, X.; Lasanajak, Y.; Tappert, M. M.; Air, G. M.; Tiwari, V. K.; Cao, H.; Chokhawala, H. A.; Zheng, H.; *Cummings, R. D.; *Smith, D. F.
A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses. 
J. Biol. Chem. 
2011, 286, 31610-31622. PMID: 21757734. PMCID: PMC3173124

87. Ding, L.; Yu, H.; Lau, K.; Li, Y.; Muthana, S.; Wang, J.; *Chen, X.
Efficient chemoenzymatic synthesis of sialyl Tn antigen and derivatives. 
Chem. Commun. 
201147, 8691-8693. PMID: 21725542. Web-themed issue on Glycochemistry & Glycobiology. PMCID: PMC3201767.[Supporting Information]

86. Urban, I.; Santurio, L. B.; Chidichimo, A.; Yu, H.; Chen, X.; Mucci, J.; Aguero, F.; *Buscaglia, C. A.
Molecular diversity of the Trypanosoma cruzi TcSMUG family of mucin genes and proteins.
Biochem. J. 2011438, 303-313. PMID: 21651499.

85. Pourceau, G.; *Chevolot, Y.; Goudot, A.; Giroux, F.; Meyer, A.; Moules, V.; Lina, B.; Cecioni, S.; Vidal, S.; Yu, H.; Chen, X.; Ferraris, O.; Praly, J.-P.; Souteyrand, E.; Vasseur, J.-J.; Morvan, F.
Measurement of enzymatic activity and specificity of human and avian influenza neuraminidases from whole virus by glycoarray and MALDI-TOF mass spectrometry. 
Chem. Bio. Chem. 
201112, 2071-2080. PMID: 21739555. [Supporting Information]

84. Thon, V.; Lau, K.; Yu, H.; Tran, B. K.; *Chen, X.
PmST2 – A novel Pasteurella multocida glycolipids alpha 2-3-sialyltransferase. 
Glycobiology 
201121, 1206-1216. PMID: 21515586. PMCID: PMC3150114. [Supporting Information]

83. Yu, H.; Cao, H.; Tiwari, V. K.; Li, Y.; *Chen, X.
Chemoenzymatic synthesis of C8-modified sialic acids and related alpha 2-3- and alpha 2-6-linked sialosides. 
Bioorg. Med. Chem. Lett. 
201121, 5037-5040. PMID: 21592790. PMCID: PMC3156331. doi: 10.1016/j.bmcl.2011.04.083.

82. Li, Y.; Cao, H.; Dao, N.; Luo, Z.; Yu, H.; Chen, Y.; Baumgarth, N.; Cardona, C.; *Chen, X.
High-throughput neuraminidase substrate specificity study of human and avian influenza viruses. 
Virology 
2011415, 12-19. PMID: 21501853. PMCID: PMC3114948.

81. Chen, G.-Y.; Chen, X.; King, S.; Cavassani, K. A.; Cheng, J.; Zheng, X.; Cao, H.; Yu, H.; Qu, J.; Fang, D.; Wu, W.; Bai, X.-F.; Liu, J.-Q.; Woodiga, S. A.; Chen, C.; Sun, L.; Hogaboam, C. M.; Kunkel, S. L.; *Zheng, P.; *Liu, Y.
Amelioration of sepsis by inhibiting sialidase-mediated disruption of CD24-Siglec G interaction.
Nat. Biotechnol. 201129, 428-435. PMID: 21478876. [Supporting information]

80. Padler-Karavani, V.; Hurtado-Ziola, N.; Pu, M.; Yu, H.; Huang, S.; Muthana, S.; Chokhawala, H. A.; Cao, H.; Secrest, P.; Friedmann-Morvinski, D.; Singer, O.; Ghaderi, D.; Verma, I. M.; Liu, Y.-T.; Messer, K.; Chen, X., *Varki, A., Schwab, R.
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer. 
Cancer Res. 
201171, 3352-3363. PMID: 21505105.PMCID: PMC3085609[Supporting information]

79. Sela, D. A.; Li, Y.; Lerno, L.; Wu, S.; Marcobal, A. M.; German, B. J.; Chen, X.; Lebrilla, C. B.; *Mills, D. A.
An infant-associated bacterial commensal utilizes human milk sialyloligosaccharides. 
J. Biol. Chem.
 2011286, 11909-11918. PMID: 21288901.PMCID: PMC3069393. [Supporting information]

78. Lau, K.; Yu, H.; Thon, V.; Khedri, Z.; Leon, M. E.; Tran, B. K.; *Chen, X.
Sequential two-step multienzyme synthesis of sialyl T antigens and derivatives. 
Org. Biomol. Chem.
 20119, 2784-2789.
 PMID: 21359399. PMCID: PMC3114947. [Supporting information]

77. *Cao, H.; Hwang, J.; *Chen, X.
Carbohydrate-containing natural products in medicinal chemistry.
In Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry. Vinod K. Tiwari Ed.2011, 411-431.

76. Yu, H.; *Chen, X.
Chapter 10. Combinatorial biosynthesis of complex carbohydrates.
In Carbohydrate Recognition: Biological Problems, Methods, and Applications. Binghe Wang, Geert-Jan Boons Eds. 2011, 229-255. Wiley.

75. Huang, S.; Yu, H.; *Chen, X.
Efficient chemoenzymatic synthesis of sialosides.
Science China Chemistry 201154, 117-128. PMID: 21686057. PMCID: PMC3115702.

74. *Chen, X.
Fermenting next generation glycosylated therapeutics. 
ACS Chem. Biol.
 An invited Point of View report. 20116, 14-17. PMID: 21250649.

73. Sugiarto, G.; Lau, K.; Yu, H.; Vuong, S.; Thon, V.; Li, Y.; Huang S.; *Chen, X.
Cloning and characterization of a viral alpha2-3-sialyltransferase (vST3Gal-I) for the synthesis of sialyl Lewis x. 
Glycobiology 
2011, 21, 387-396. PMID: 20978012. PMCID: PMC3033747 [Supporting information]

72. Li, Y.; Cao, H.; Yu, H.; Chen, Y.; Lau, K.; Qu, J.; Thon, V.; Sugiarto, G. *Chen, X.
Identifying specific sialidase inhibitors for human cytosolic sialidase NEU2 by substrate specificity studies. 
Mol. Biosyst. 
2011,7, 1060-1072. PMID: 21206954.PMCID: PMC3114945[Supporting information]

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