2012

106. Canepa, G. E.; Mesias, A. C.; Yu, H.; Chen, X.; *Buscaglia, C. A.
Structural features affecting trafficking, processing, and secretion of Trypanosoma cruzi mucins. 
J. Biol. Chem
. 2012287, 26365-26376. PMID: 22707724. PMCID: PMC3406720

105. ‡Khedri, Z.; ‡Li, Y.; Cao, H.; Qu, J.; Yu, H.; Muthana, M. M.; *Chen, X. 
Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2.
Org. Biomol. Chem.
 2012, 10, 6112-6120. PMID: 22641268. ‡Co-first authors.

104. ‡Padler-Karavani, V.; ‡Song, X.; Yu, H.; Hurtado-Ziola, N.; Huang, S.; Muthana, S.; Chokhawala, H. A.; Cheng, J.; Verhagen, A.; Langereis, M. A.; Kleene, R.; Schachner, M.; de Groot, R. J.; Lasanajak, Y.; Matsuda, H.; Schwab, R.; Chen, X.; Smith, D. F.; Cummings, R. D.; Varki, A.

Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays. 
J. Biol. Chem. 
2012287, 22593-22608. PMID: 22549775. PMCID: PMC3391140. ‡Co-first authors.

103. ‡Sugiarto, G.; ‡Lau, K.; Qu, J.; Li, Y.; Lim, S.; Mu, S.; Ames, J. B.; *Fisher, A. J.; *Chen, X.
A sialyltransferase mutant with decreased donor hydrolysis and reduced sialidase activities for directly sialylating Lewis x. 
ACS Chem. Biol. 
20127, 1232-1240. PMID: 22583967. ‡Co-first authors.

102. Yu, H.; Lau, K.; Li, Y.; Sugiarto, G.; *Chen, X. 
One-pot multienzyme synthesis of Lewis x and sialyl Lewis x antigens. Invited Protocol. 
Curr. Protoc. Chem. Biol. 
Accepted.

101. Lu, Q.; Padler-Karavani, V.; Yu, H.; Chen, X.; *Wu, S.-L.; *Varki, A.; Hancock, W. S.
LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies Immmunoglobulin G subclass and partial sequence using multistep Intravenous Immunoglobulin affinity purification and multienzymatic digestion. 
Ana. Chem.
 2012, 84, 2761-2768. PMID: 22390546.

Li, Y.; *Chen, X.
Sialic acid metabolism and sialyltransferases, natural functions and applications. Invited Mini-Review.
Appl. Microbiol. Biotechnol. 94, 887-905. PMID: 22526796.

99. ‡Khedri, Z.; ‡Muthana, M. M.; ‡Li, Y.; Muthana, S.; Yu, H.; Cao, H.; *Chen, X. 
Probe sialidase substrate specificity using chemoenzymatically synthesized sialosides containing C9-modified sialic acids.
Chem. Commun. 2012, 48, 3357-3359. PMID: 22361713 ‡Co-first authors.

98. ‡Muthana, M. M.; ‡Qu, J.; Li, Y.; Zhang, L.; Yu, H.; Ding, L.; Malekan, H.; *Chen, X. 
Efficient one-pot multienzyme synthesis of UDP-sugars using a promiscuous UDP-sugar pyrophosphorylase from Bifidobacterium longum (BLUSP). 
Chem. Commun. 
201248, 2728-2730. PMID: 22306833 ‡Co-first authors.

97. Thon, V.; Li, Y.; Yu, H.; Lau, K.; *Chen, X.
PmST3 from Pasteurella multocida encoded by Pm1174 gene is a monofunctional alpha 2-3- sialyltransferase. 
Appl. Microbiol. Biotechnol. 
201294, 977-985. PMID: 22075637.

96. Li, Y.; Yu, H.; Cao, H.; Muthana, S.; *Chen, X. 
Pasteurella multocida
 CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity.
Appl. Microbiol. Biotechnol201293, 2411-2423. PMID: 21968653. 

95. Linman, M. J.; Yu, H.; Chen, X.; Cheng, Q.
Chapter 13. Surface plasmon resonance imaging analysis of protein binding to a sialoside-focused carbohydrate microarray.
In Methods in Molecular Biology series Carbohydrate Microarrays: Methods and Protocols. Edited by Yann Chevolot. 2012808, 183-194. PMID: 22057526. [link]

94. *Cao, H.; *Chen, X.
Chapter 3. General consideration on sialic acid chemistry.
In Methods in Molecular Biology series Carbohydrate Microarrays: Methods and Protocols. Edited by Yann Chevolot. 2012808, 31-56. PMID: 22057516. [link]

Advertisements